ea0036oc7.2 | Oral Communications 7 | BSPED2014
Bulwer Chloe
, Mills Kevin
, Sirka Ernestas
, Hindmarsh Peter
Background: Oxidative stress has been implicated in the development and progression of complications in type 1 diabetes (T1DM). Vitamin E (α-tocopherol) undergoes β-oxidation of its chomanol ring and the resulting metabolite α-TLHQ has been proposed as a potential biomarker of oxidative stress. HbA1c relates in T1DM to microvascular complications predominantly although the end-points are late in disease development. The oxidative stress process may act independe...